{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Drugs - Ocular Drugs I MYDRIATIC DRUGS 1 Phenylephrine...

Info icon This preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Ocular Drugs I. MYDRIATIC DRUGS 1. Phenylephrine Hydrochloride a. Percentage used: 2.5%, 5% and 10% as eye drops b. Group: Sympathomimetic, alpha adrenergic agonist c. Mechanism of Action: Acts directly on alpha receptors on- Dilator pupillae causing mydriasis Conjunctival arterioles causing vasoconstriction and blenching of conjunctiva Its action can be reversed by 0.1% thymoxamine d. Indications: i. For dilatation of pupil for diagnostic purposes ii. For mydriasis for doing refraction iii. Before intraocular surgery iv. For confirmation of diagnosis of Horner’s syndrome e. Side effects i. Ocular- stinging , burning, maculopathy with a central scotoma (rare) results from use in aphakic patients and rebound miosis ii. Systemic: CVS – palpitation, tachycardia, cardiac arrhythmia, hypertension, headache , myocardial ischemia, stroke f. Contraindications for use:
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
i. Hypersensitivity ii. Narrow angle glaucoma iii. Long standing insulin dependent diabetes iv. Hypertensive patients receiving reserpine or gaunethidine 2. Tropicamide a. Percentage used: 0.5% or 1.0% as eye drops b. Group: Anticholinergic, blocks effect of acetylcholine released from cholinergic nerve endings at iris sphincter and ciliary muscles Action: (i) Mydriasis (ii) Cycloplegia c. Indications: i. For dilatation of pupil for diagnostic purposes ii. For achieving mydriasis and cycloplegia for doing refraction (retinoscopy) iii. Before intraocular surgery and post operatively for causing mydriasis and cycloplegia and to prevent synechiae formation iv. Uveitis (to prevent formation of posterior synechiae and achieving mydriasis/ cycloplegia) v. For provocative test for angle closure glaucoma
Image of page 2
It is short acting, action last for 6-8 hours d. Side effects (i) are rare; its safe for use in cardiac and hypertensive patients e. Contraindications for use: i. Narrow angle glaucoma 3. Atropine Sulphate a. Percentage used: 0.5% and 1% as eye drops; and 1% eye ointment b. Group: Parasympatholytic (anticholinergic) c. Mechanism of Action: Blocks response of sphincter and ciliary muscles to cholinergic stimulation causing mydriasis and cycloplegia It is strongest mydriatic Mydriatic effect begins in 30 min, last 7 -10 days; Cycloplegic effect begins in 60 – 90 min, last 7 -10 days d. Indications: i. Cycloplegic refraction (usually in children below the age of five years) ii. Uveitis/ Iridocyclitis iii. Penalisation ,for treatment of amblyopia (alternative to occlusion therapy) e.
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern