Giant Cell Tumor of Bone-1

Giant Cell Tumor of Bone-1 - Giant Cell Tumor of Bone...

Info iconThis preview shows pages 1–11. Sign up to view the full content.

View Full Document Right Arrow Icon
Giant Cell Tumor of Bone
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Overview Definition Epidemiology Hx Presentation/Exam Radiology Dx Tx Outcomes
Background image of page 2
Definition 1 0 bone neoplasm First described Cooper 1818 Lebert microscopic description 1845 Generally benign Potential for : Recurrence Pulmonary metastasis Frank malignancy
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Epidemiology 5-10% 1 0 bone tumors 20% benign bone tumors F : M 1.5 : 1 70-80% age 20-40 Rare skeletally immature Epiphyseal Monostotic
Background image of page 4
Incidence Ends of long bones >50% about knee High recurrence rate 1-2% benign pulm. Mets 1 0 malignant GCT <1% Rare polyostotic form <1%
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Location
Background image of page 6
Presentation Pain x wks. – mos. Swelling Mass Pathologic # Neuro deficit (spine / sacrum) incidental
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Radiology Lytic lesion Epipyseal Eccentric or central Narrow zone transition Cortical thinning expansile No sclerotic margin
Background image of page 8
Imaging Occ. Cortical breakthrough +/- soft tissue mass Extend to subarticular cortex Typically no host response Often large @ presentation
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Other modalities CT Integrity cortical rim MRI Assess subchondral breakthrough Bone Scan Suspect multicentri loci ie. HAND
Background image of page 10
Image of page 11
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

Page1 / 40

Giant Cell Tumor of Bone-1 - Giant Cell Tumor of Bone...

This preview shows document pages 1 - 11. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online