giantcell - Temporal artery biopsy within a week of...

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1 GIANT CELL ARTERITIS (Temporal or Cranial Arteritis) Idiopathic vasculitis Same disease spectrum as polymyalgia rheumatica Mainly women 65-80 years old Medium and large arteries in head & neck involved
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2 GIANT CELL ARTERITIS Presentation Headache Scalp tenderness Thickened temporal arteries Jaw claudication Acute visual loss Weight loss, anorexia, fever, night sweats, malaise & depression
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3 GIANT CELL ARTERITIS Ocular Complications Transient monocular visual loss (amaurosis fugax) Visual loss due to Central retinal artery occlusion (CRAO) or Anterior ischaemic optic neuropathy (AION) Visual field defects
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4 GIANT CELL ARTERITIS Management ESR if suspected Start high dose steroids immediately to prevent stroke or second eye involvement
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Unformatted text preview: Temporal artery biopsy within a week of starting steroids 5 GIANT CELL ARTERITIS Temporal Artery Biopsy Arteries have skip lesions ultrasound/Doppler may help identify involved areas If positive, confirms diagnosis helpful in management of future disease If negative, doesnt exclude diagnosis, but need to think about an alternative diagnosis 6 GIANT CELL ARTERITIS Histopathology Granulomatous cell infiltration Giant cells Disruption of internal elastic lamina Proliferation of intima Occlusion of lumen 7 GIANT CELL ARTERITIS Treatment Intravenous and oral steroids prolonged course of steroids often necessary...
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giantcell - Temporal artery biopsy within a week of...

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