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Unformatted text preview: ruary 5, 1981 Case report of using long term lasix therapy
in the treatment of SIADH for 12weeks. Effect of Lasix on serum Na
Effect Use of lithium in SIADH
• Lithium-induced Downregulation of Aquaporin-2
• Water Channel Expression in Rat Kidney
Lithium treatment reduced AQP2 expression
dramatically, to 31±8% after 10 d coincident
with development of severe polyuria.
Administration of DDAVP / water deprivation and
stopping lithium only partially reversed the
(J.Clin. Invest. 1995. 95:1838-1845) Use of Demeclocycline
• Small study comparing use of demeclocycline
• and lithium- 10 patients with Na -120-122
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.
- Fall '11