Guidelines for blood grouping and red cell antibody 3.57.51 PM

Guidelines for blood grouping and red cell antibody 3.57.51 PM

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Guidelines for blood grouping and red cell antibody testing during pregnancy Transfusion Medicine, BCSH
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INTRODUCTION ABO Rh D-typing and antibody screen tests on the sera of the pregnant women are performed for the protection of the mother and the identification of HDN The guidelines are addressed to the hematology unit undertaking such antenatal testing. It is accepted that samples should be tested only when it is likely that results could influence the clinical management of the pregnancy.
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OBJECTIVES 1) The objectives of routine serological testing are: a) Identify pregnancies at risk of fetal and neonatal HDN b) Identify RhD-negative women who need anti-D Ig prophylaxis c) Provide compatible blood swiftly for obstetric emergencies .
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OBJECTIVES 2) When red cell ab are present, the purpose of f/u serological tests are: a) identify the fetus that may need treatment before term b) predict infants who are likely to require treatment for HDN in the neonatal period c) identify any additional red cell allo ab developing during the course of the current pregnancy. d) identify additional maternal ab induced by intrauterine red cell transfusions
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Testing protocols 1) All pregnant women The first antenatal examination at booking is usually at 10-16 wks POA- test for ABO and RhD gp and presence of red cell alloab When an ab screen is +, further testing sh be carried out to determine ab specificity and significance. Subjects who have weak RhD blood groups are RhD + & do not form immune anti-D
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Cont: It is essential that pt with ab of clinical significance sh be referred for advice to a specialist at the earliest oppurtunity
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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Guidelines for blood grouping and red cell antibody 3.57.51 PM

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