hiv - Ocular manifestations of HIV infection Introduction...

Info iconThis preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Ocular manifestations of HIV infection Introduction AIDS is an infectious disease caused by the gradual decrease in CD4+ T lymphocytes causing subsequent opportunistic infections and neoplasia. It is a blood borne and sexually transmitted infection caused by the HIV (Human Immunodeficiency Virus) Approximately 36 million persons around the world are infected. Up to 70% of patients infected with HIV will develop some form of ocular involvement, ie: direct infection by HIV,opportunistic infections and neoplasia. HIV infection progresses though different phases Ocular manifestations correlating with immune status and stage of HIV infection When the CD4+ count deteriorates, the immune system fails and symptoms such as malaise, night malaise, night sweats, fever and loss of sweats, fever and loss of weight weight develop as the infection progresses. Measuring the absolute CD4+ count is an essential part of the staging the disease. tage CD4+ External eye Anterior segment Posterior segment Neuro-ophthalmic eroconversion 1000 Inflammed conjunctiva Dry eye Headache Retro-orbital pain arly HIV infection 500-1000 Allergic conjunctivitis Reiters syndrome Intermediate uveitis Retinal vasculitis HIV retinopathy Optic neuropathy Intermediate infection 200-500 Dry eye Blepharitis Bacterial and follicular conjunctivitis Kaposis sarcoma Molluscum contagiosum Herpes zoster Herpes simplex HIV retinopathy Tberculous uveitis Aspergillosis ate 0-200 Opprtunistic infections and tumours affecting all ocular structures dapted from and with curtesy of PJ McCluskey: Overview of HIV infection nd pre-AIDS ocular manifestations, HIV and the eye, S Lightman ED, Imperial ollege Press London, 2000 Ophthalmic Manifestations of HIV Infection AROUND THE EYE Molluscum Contagiosum Herpes Zoster Ophthalmicus Kaposis Sarcoma Conjunctival Squamous Cell Carcinoma Trichomegaly FRONT OF THE EYE Dry Eye Anterior Uveitis BACK OF THE EYE Retinal Microvasculopathy CMV Retinitis Acute Retinal Necrosis Progressive Outer Retinal Necrosis Toxoplasmosis Retinochoroiditis Syphilis Retinitis Candida albicans endophthalmitis NEURO-OPHTHALMIC Molluscum Contagiosum Molluscum contagiosum is a viral infection of the skin. Affects up to 20% of symptomatic HIV infected patients. Clinically appears like painless, painless, small, small, umbilicated umbilicated nodules nodules, which produce a waxy discharge waxy discharge when pressured. Treatment consists on excision excision of the lesion, curettage curettage or cryotherapy cryotherapy Herpes Zoster Ophthalmicus Due to the reactivation of a latent infection by Varicella Varicella Zoster Virus Zoster Virus in the dorsal root of trigeminal nerve ganglion trigeminal nerve ganglion....
View Full Document

Page1 / 35

hiv - Ocular manifestations of HIV infection Introduction...

This preview shows document pages 1 - 9. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online