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HP - Helicobacter Pylori and Helicobacter Hyperemesis...

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Emam 2003 BY BY Prof. Dr. Prof. Dr. Mohammad A. Emam Mohammad A. Emam Prof. of Obstetrics and Gynecology Prof. of Obstetrics and Gynecology Mansoura Faculty of Medcine Mansoura Faculty of Medcine Mansoura Integrated Fertility Center Mansoura Integrated Fertility Center (MIFC) – EGYPT (MIFC) – EGYPT Helicobacter Pylori and Helicobacter Pylori and Hyperemesis Gravidarum Hyperemesis Gravidarum
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Emam 2003 Rationale Rationale Hyperemesis Gravidarum is usually a vexing problem for obstetricians Especially When conventional supportive therapy fails.
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Emam 2003 Hyperemesis gravidarum (H.G) Is the most severe manifestation of the spectrum of nausea and vomiting of pregnancy. It complicates from 0.3 to 2% of all pregnancies ( Broussard & Richter, Broussard & Richter, 1998 and Hod et al., 1994 1998 and Hod et al., 1994 ).
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Emam 2003 Materno – Fetal Morbidity Materno – Fetal Morbidity 1) Dehydration, electrolyte imbalance, and acid base disturbances may lead to renal and hepatic injury (Eliakim et al., 2000).
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Emam 2003 Materno – Fetal Materno – Fetal Morbidity Morbidity cont… cont… 2) Patients who manifest continuous weight loss and electrolyte distrurbances may be at risk for growth restriction, fetal anomalies and decreased neonatal birth weight ( Gross et al., 1989 and Tincello & Gross et al., 1989 and Tincello & Johnston, 1996 Johnston, 1996 ).
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Emam 2003 Risk Factors for HG Risk Factors for HG Pgda Multiple pregnancy. Young age (>24). PH of HG. Obesity.
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Emam 2003 Causes of HG Causes of HG Theories: Theories: High levels of hCG ( multiple – molar). Increased estrogen levels. Psychological factors. High-fat diet. PG. Helicobacter pylori(HP) ???
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Emam 2003 What is What is Helicobacter pylori ? ? Is a spiral-shaped gram negative rods found on gastric mucosa particularly the antrum (Howden, 1996). Helicobacter P
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Emam 2003
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Emam 2003 Very common all over the world 55% ( WU et al 2000 ) 90% In peptic ulcer. 60% - 80% in gestritis without ulcer. Developing > developed. In Egypt very common at young age (65%) (Bassily et al 1994…) Prevalence of HP Prevalence of HP
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Emam 2003 Transmission HP Transmission HP Oral – Oral.
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