hypertension - HYPERTENSIVE RENAL DISEASE IN AFRICAN...

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HYPERTENSIVE RENAL DISEASE IN AFRICAN AMERICANS AND ROLE OF GENETIC FACTORS SONIKA PURI
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EPIDEMIOLOGY HTN is cited as a cause of ESRD in 30% cases; In AA population it is second leading cause of esrd. Incidence of esrd sec. to htn is 5 fold higher in AA. ERSD due to HN (hypertensive nephropathy ) occurs at a younger age in AA compared to non AA population. Factors such as – lack of access to health care, severity and duration of htn, etoh and drug use, educational status. NHANES 2 indicates that after adjusting for socioeconomic/modifiable factors RR of progression to ESRD is still 1.96 times higher in AA. Hypertensive nephrosclerosis in AA, Toto, KI 2003
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FAMILIAL RISK OF ESRD IN AA. FREEDMAN ET AL, AJKD 1993 Family history of 131 AA pts with ESRD compared with 115 age/sex and race controlled non-esrd patients. 40% pts with HN ( 12/30), 32% of type 2 DM ( 18/51) and 13% of CGN pts had first-, second- or third-degree relative with ESRD. Presence of a first-degree relative increased an AA risk of have ESRD ninefold (OR 9.13, CI 2.2-12.3, p <0.005). Gender differences among Ors were non significant, also no difference in SE class/education among cases and controls.
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HYPERTENSIVE NEPHROSCLEROSIS AMONG AA VS.CAUCASIANS. MARCANTONI ET.AL, KI 2002
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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hypertension - HYPERTENSIVE RENAL DISEASE IN AFRICAN...

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