Introduction to Genetic 3.57.51 PM

Introduction to Genetic 3.57.51 PM - IntroductiontoGenetic...

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Introduction to Genetic Dr Rosline Hassan Department of Haematology School of Medical Sciences University Sains Malaysia
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Table of contents Chromosome DNA Protein synthesis Mutation Genetic disorder Relationship between genes and cancer Genetic testing Technical concern 
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Chromosome  All living organisms  consist of cells. In each cell there is  chromosomes . Chromosomes are  strings of DNA  Chromosome consists  of  genes , blocks of  DNA.  Each gene encodes a  particular protein. 
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Chromosome Each gene has its own position in the  chromosome. This position is called  locus Complete set of genetic material (all  chromosomes) is called  genome Particular set of genes in genome is called  genotype The genotype is with later development after  birth base for the organism's  phenotype , its  physical and mental characteristics, such as  eye color, intelligence etc.
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DNA DNA is a double  helix composed of  two intertwined  nucleotide chains  oriented in opposite  directions. The double helix  composed of  building block called  nucleotides
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DNA Each nucleotides  consist : Phosphate group Deoxyribose sugar  molecule One of four different  nitrogenous bases  either  Purines - Adenine and Guanine, or Pyrimidines -Cytosine and Thymine)
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DNA The functional units of DNA are genes. A gene is a segment of DNA that can be  copied to make RNA. The nucleotide sequence in RNA is translated  into the amino acid sequence of a protein. Proteins are the main determinants of the  basic structural and physiological properties  of an organism.
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Protein synthesis DNA is duplicated  before a cell divides A process called  replication
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Protein synthesis Genes are transcribed into  RNA ( transcription ).  Non-coding parts are  removed called mRNA Transported out of the  nucleus  Outside the nucleus, the  proteins are built ( translation ).
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Mutation  Mutations Inherited Carrier or diseased Acquired  Caused by radiation, toxins, diet,  infections
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Mutation Variation within a species may be from  hereditary variation, environmental variation,  or both. The newly created offspring can then be 
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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Introduction to Genetic 3.57.51 PM - IntroductiontoGenetic...

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