IUGR and IUFD - IUGR IUFD DR SALWA NEYAZI CONSULTANT...

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DR. SALWA NEYAZI CONSULTANT OBSTETRICIAN GYNECOLOGIST PEDIATRIC & ADOLESCENT GYNECOLOGIST
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IUGR What is the definition of IUGR? < 10th centile for age include normal fetuses at the lower ends of the growth curve + fetuses with IUGR This definition is not helpful clinically < 5th centile for age < 3rd centile for age the most appropriate definition but associated with adverse perinatal outcome
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? SGA < 10th centile for the population, which means it is at the lower end of the normal distribution ie. Constitutionally small but have reached their full growth potential IUGR Failure of the fetus to chieve the expected weight for a given gestation
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What are the causes of IUGR ? Maternal medical conditions Chromosomal anomalies & aneuploidy 1ry placental disease Extremes of maternal age Low socioeconomic status Infections Multiple gestation
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Which maternal medical conditions result in IUGR? HPT PET DM with vascular involvement SLE Anemia Sickle cell disease Antiphospholipid syndrome Renal disease Malnutrition Inflammatory bowel disease Intestinal parasites Cyanotic pulmonary disease
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How does the placenta play a role in the development of IUGR ? invasion Idiopathic or due to maternal disease eg SLE, PET, DM, HPT Chronic partial abruption Placental infarcts Placenta previa Chorioangioma Circumvallate placenta Placental mosaicism Twin to twin transfusion Syndrome
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What infections result in IUGR ? Congenital infections: CMV Rubella Herpes Vericella zoster Toxoplasmosis Malaria Listeriosis 5-10% of IUGR
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Which drugs can result in IUGR? Alcohol Cigarette smoking 3-4X Methotrexate Anticonvulsants Warfarin Antihypertensives /ß-blockers Cyclosporin
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Down’s syndrome T21 Trisomy 13,18 Turner syndrome Neural tube defects Achondroplasia Osteogenisis imperfecta Abdominal wall defects Duodenal atresia Renal agenesis/ Poter’s S 15% of IUGR Symmetric IUGR AFV/ Doppler N Structural abnormalities
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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IUGR and IUFD - IUGR IUFD DR SALWA NEYAZI CONSULTANT...

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