kawasaki - MI in KAWASAKIS DISEASE E.J.Lovett, Jr. MD WRAMC...

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E.J.Lovett, Jr. MD WRAMC MI in KAWASAKI’S DISEASE MI in KAWASAKI’S DISEASE
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E.J.Lovett, Jr. MD WRAMC Epidemiology of Kawasaki’s Epidemiology of Kawasaki’s 80% 0f patients are under 5 yrs of age Male/female= 1.5 U.S. attack rate 1/10,000 Attack rate for Asians 6/10,000 Attack rate for African American 1.5/10K 2%die during subacute or conval. stage from acute thrombosis of aneurys. CA’s
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E.J.Lovett, Jr. MD WRAMC CORONARY ARTERY CORONARY ARTERY ANEURYSMS ANEURYSMS Diffuse dilation of CA’s during the acute phase in 30-50% of patients. Aneurysms persist in 15-20%, reduced to < 5% if gammaglobulin used in the acute phase. Most commonly in LCA>LAD>RCA 50% regress to no observable lesion.
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E.J.Lovett, Jr. MD WRAMC CORONARY ARTERY CORONARY ARTERY ANEURYSMS ANEURYSMS In 25%, aneurysms persist but reduced in size. In 25%, aneurysmy heal to severe stenosis or complete occlusion. Of all pats. with aneurysms, 7-10% have MI. Giant aneurysms(> 8mm) during the acute phase at highest risk for MI.
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E.J.Lovett, Jr. MD WRAMC Myocardial Infarction Myocardial Infarction Onset: 40% within 3 months 73% within first yr. 20% occur more than 2 yrs out 5% greater than 6 yrs Symptoms:63% had symptomatic MI 54% presented in shock chest pain:<4yr20%, >4yr 80%
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E.J.Lovett, Jr. MD
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kawasaki - MI in KAWASAKIS DISEASE E.J.Lovett, Jr. MD WRAMC...

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