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Unformatted text preview: Oropharyngeal and Oral
Cancer Tiffany Lindholm What is oral cancer?
Cancer of the mouth (oral cavity)
inside lining of the lips and cheeks
front two-thirds of the tongue
area behind the wisdom teeth What is Oropharyngeal Cancer?
Cancer in the throat (oropharynx)
begins where oral cavity stops
Base of tongue
tonsils and tonsillar pillars
back wall of throat Uses of oral cavity and oropharynx
Salivary glands make saliva to keep mouth
moist and helps digest food
moist What causes the cancer?
Exposure to ultraviolet radiation
DNA malfunction Key statistics
28,260 new cases is 2004
7,230 (4,830 men and 2,400) people will die in
More frequent in Blacks than whites
81% survive 1 year after diagnosis
For all stages combined 56% survive 5 years
41%survive 10 years
If cancer found early 80% survive 5 years Key statistics
More common in Hungary and France
15% Newly diagnosed patients will have
10-40% will develop a second cancer Signs and symptoms
Sore in the mouth that doesn’t heal
Pain that doesn’t go away
Lump or thickening in the cheek
White or red patch on gums, tongue, tonsil or lining of
Difficulty chewing, swallowing, moving jaw or tongue
Loosening of the teeth
Lump or mass in the neck
Persistent bad breath Treatment options
Stage 0: Surgery 95-100%
Stages 1 and 2: Surgery or radiation 6080%
Stages 3 and 4: Surgery and radiation or
radiation and chemotherapy or all three
20-50% Side effects
Laryngectomy After treatment
Speech and swallowing therapy
Follow up tests
Chemo prevention What’s new?
Tumor growth factors
Gene therapy ...
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- Fall '11