PHLYCTENULAR Conjunctivits

PHLYCTENULAR Conjunctivits - PHLYCTENULAR...

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PHLYCTENULAR KERATO-CONJUNCTIVITIS
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October 16, 2006 Dr Sanjay Shrivastava 2 Definition Phlyctenular kerato-conjunctivitis (PKC) is characteristic nodular affection occurring mainly in children as an allergic response of the corneal and conjunctival epithelium to endogenous toxin to which the tissue has become sensitized. Phlycten means Blister.
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October 16, 2006 Dr Sanjay Shrivastava 3 Epidemiology World-wide, sporadic. Most commonly found in the young in the first and second decades of life with peak between ages 3 and 15. Usually higher incidence in girls than in boys. Most commonly found in the undernourished who live in poor and overcrowded unhygienic conditions, not exposed adequately to sunlight. More common in poorer quarters of the cities, affecting all races.
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October 16, 2006 Dr Sanjay Shrivastava 4 Etiology Phylectenules are an allergic phenomenon, a reaction of the hypersensitive of epithelium of the cornea and conjunctiva to any protein; the reaction is essentially non-specific but in the majority of clinical cases due to tubercular proteins. Staphylococcus aureus may also act in this way in highly sensitive patients. May also occur in patients with metastatic endogenous gonococcal conjunctivitis.
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October 16, 2006 Dr Sanjay Shrivastava 5 Pathology Granulation tissue with fibroblasts and blood vessels are common in the areas of
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PHLYCTENULAR Conjunctivits - PHLYCTENULAR...

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