renal - Renal Physiology D. C. Mikulecky Faculty Mentoring...

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12/24/11 Renal Physiology D. C. Mikulecky Faculty Mentoring Program Virginia Commonwealth Univ.
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12/24/11 FUNCTIONS OF THE KIDNEY Water balance Electrolyte balance Plasma volume Acid-base balance Osmolarity balance Excretion Hormone secretion
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12/24/11 THE URINARY SYSTEM Kidneys Blood supply: Renal arteries and veins Ureter Urinary bladder Urethra
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12/24/11 THE NEPHRON IS THE FUNCTIONAL UNIT OF THE KIDNEY Bowman’s Capsule Glomerulus Proximal Convoluted Tubule Distal Convoluted Tubule Loop of Henle Cortex Medulla Artery Vein Peritubular Capillaries Collecting Duct
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12/24/11 THREE BASIC RENAL PROCESSES Glomerular Filtration: Filtering of blood  into tubule forming the primitive urine Tubular Reabsorption: Absorption of  substances needed by body from tubule to  blood Tubular Secretion: Secretion of  substances to be eliminated from the body  into the tubule from the blood
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12/24/11 BASIC RENAL PROCESSES GF TR TA Urine Excreted Efferent Arteriole Afferent Arteriole Glomerulus Kidney Tubule Peritubular Capillary
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12/24/11 Glomerular Filtration First step in urine formation 180 liters/day filtered Entire plasma volume filtered 65 times/day Proteins not filtered
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12/24/11 Forces Involved in Glomerular Filtration Glomerular Capillary Blood Pressure + 55 Plasma Colloid Osmotic Pressure - 30 15 10 Bowman’s Capsule Hydrostatic Pressure - Net Filtration Pressure +
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12/24/11 Tubular Reabsorption Water: 99% reabsorbed Sodium: 99.5% reabsorbed Urea: 50% reabsobed Phenol: 0% reabsorbed
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renal - Renal Physiology D. C. Mikulecky Faculty Mentoring...

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