Schistosomiasis - 4/8/08 Brad Weaver Schistosome Parasitic...

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4/8/08
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Brad Weaver
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Schistosome Parasitic blood fluke of trematode family Prevalent in tropics – 200 million people affected Acute infection - swimmer’s itch and Katayama fever Chronic infection – deposited eggs invade tissue and get lodged in portal circulation causing inflammation and fibrosis Two types of renal disease Urinary obstruction from S. haematobium Immune complex deposition disease from other species
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S. haematobium Direct invasion of urinary system Acquired in North Africa, Turkey, the Middle East, and India Eggs migrate from vesical venous plexus into bladder wall and then are excreted in urine Often presents with hematuria Chronic inflammation and fibrosis of bladder wall can cause: Hydronephrosis and calcification of urinary tract Bladder cancer
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S. mansoni and S. japonicum Acquired in tropical areas of Africa, Asia, South America, and the Caribbean Eggs released from mesenteric venous plexus can travel
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Schistosomiasis - 4/8/08 Brad Weaver Schistosome Parasitic...

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