Chapter 18 Gas Exchange and Transport

Chapter 18 Gas Exchange and Transport - Ch 18 Gas Exchange...

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Ch 18: Gas Exchange and Ch 18: Gas Exchange and Transport Transport Dissolve CO Dissolve CO 2 2 for transport for transport Transport O Transport O 2 2 – role of hemoglobin – role of hemoglobin Transport CO Transport CO 2 Regulate ventilation Regulate ventilation Running Problem: High Altitude
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Diffusion and Solubility of Gases Diffusion and Solubility of Gases Diffusion most rapid over short distances At alveolar and systemic capillaries Concentration Gradient expressed as Partial Pressure Diffusion rate Surface area x conc. gradient x membr. permeability Membrane thickness Fick’s law furthers the principles of diffusion: Fig 18-1
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Partial Pressure Partial Pressure 1. = P O2 = 100 mmHg at sea level 2. Since gases can diffuse/dissolve into liquids, partial pressure allows comparison between the two media. 1. Determines concentration gradient 3. Solubility of gas depends on 1. solubility of molecule in particular liquid 2. pressure gradient 3. temperature 4. Equilibrium not necessarily the same concentration 1. CO 2 is 20x more soluble than O 2 , explains the need for Hb
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Chapter 18 Gas Exchange and Transport - Ch 18 Gas Exchange...

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