Chapters 22 and 23 Metabolism

Chapters 22 and 23 Metabolism - Chapters 22 and 23...

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Unformatted text preview: Chapters 22 and 23 Metabolism Metabolism Energy Balance Energy Based on First Law of Thermodynamics: Energy input = Energy output (work) Energy stored as glycogen and fat Work = transport, mechanical, chemical Unit of Measure: Kilocalorie (Calorie) Raise 1 L of H2O 1°C. calorie = 1 gram of H2O 1°C calorie gram Basal Metabolic Rate (BMR) in kcal/day Metabolism = sum of all chemical reactions in the body reactions Anabolic vs. catabolic Absorptive vs. Absorptive Postabsorptive Postabsorptive Recall glycolysis and Recall TCA cycle TCA Control of Metabolism Insulin and Glucagon Insulin Some consider that insulin is THE anabolic Some hormone hormone Insulin:glucagon ratio Insulin:glucagon Other Hormones (Chapter 23) Other NS Emotional factors (Running Problem) Chapter 23: Endocrine Control of Metabolism Metabolism 1. Adrenal Glands 1. Steroids (aldosterone and cortisol) 2. Thyroid 1. Accelerator Pedal? 3. Growth Hormone 1. Facilitates Growth and Development 4. PTH and Calcitonin 1. Control of [Ca2+] 1) Adrenal Glands 1) Adrenal medulla Catecholamines Adrenal Cortex Glucorticoids (controlled by ACTH) Aldosterone Anabolic steroids?? DHEA?? 2) Thyroid 2) Precursor: thyroglobulin Add iodine to make T3 and T4 and Control by TSH cTSH 3) Growth Hormone 3) Anterior Pituitary Anabolic Recently synthesized Excess = Excess Acromegaly in adults Gigantism in children Target = IGF (insulin-like growth factors) 4) Calcium 4) PTH raises Ca2+ Calcitonin lowers it Calcitriol enhances Calcitriol absorption of Ca2+ absorption AKA Vit D3 Role of estrogen?? Osteoporosis and HRT ...
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This note was uploaded on 12/24/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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