Schizophrenia-2 - Madness & Genius: Schizophrenia...

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Madness & Genius: Schizophrenia Jariel Rendell HRS 305
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Outline Schizophrenia Schizotypal traits & Creativity
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Schizophrenia Severe psychotic illness Disturbances in perception, emotion,  thought, or speech 1% Prevalence rate Positive and Negative Symptoms
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Positive Symptoms Pathologically excessive: Hallucinations Delusions Racing, disorganized Thoughts Disorganized Speech
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Negative Symptoms Pathologically deficient: Flattened Affect Alogia Poverty of speech Avolition Lack of desire, motivation, or persistence
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Predisposing Factors Genetic influences Twin studies: Monozygotic twins have 46%  concurrence rate Dizygotic twins have 14% concurrence  rate Environmental influences E.g., Prenatal Concordance rate for monozygotic (MZ)  twins sharing same placenta twice as high as  MZ twins in different placentas
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Enlarged Ventricles              Control     Schizophrenic
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Hypofrontality
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Immediate Causes of Schizophrenia Functional and structural  abnormalities in the brain Hypofrontality Enlarged ventricles Dopamine hypothesis Neurotransmitter imbalances Video
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Schizophrenia and Intelligence Did he seem intelligent? Is it possible to measure his level of  intelligence? Is he more in touch with “true” reality  than the rest of us?
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Intelligence and Schizophrenia Intelligence can be measured in  schizophrenics using IQ tests Schizophrenics have much lower IQ scores  than non-schizophrenics Badcock et al. (2005) compared  schizophrenics’ current and pre-morbid IQ 
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Schizophrenia-2 - Madness & Genius: Schizophrenia...

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