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Mumps - MUMPS OUTBREAK US 2006 RECOGNITION MANAGEMENT...

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MUMPS OUTBREAK, US, 2006: RECOGNITION, MANAGEMENT & PREVENTION IN THE HEALTHCARE SETTINGS David Jay Weber, M.D., M.P.H. Professor of Medicine, Pediatrics, & Epidemiology Medical Director, Occupational Health & Infection Control University of North Carolina at Chapel Hill
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MUMPS MICROBIOLOGY AND EPIDEMIOLOGY
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MUMPS Microbiology Paramyxovirus (single stranded RNA) Single serotype Epidemiology Prevalence: 200-300 cases in US per year (peak late winter and spring) Reservoir: Humans only Distribution: Worldwide Transmission: Droplet & contact (spread through contact with respiratory secretions and saliva or via fomites)
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VACCINE PREVENTABLE DISEASES: MAXIMUM CASES AND CURRENT PREVALENCE Disease Max. Cases (Year) # 2003 % Reduction Diphtheria 206,939 (1921) 1 99.855 Invasive Hib 20,000 (1984) 2,013 89.935 Measles 894,135 (1941) 56 99.994 Mumps 152,209 (1968) 231 99.848 Pertussis 265,269 (1934) 11,647 95.610 Polio 21,269 (1952) 0 100.000 Rubella 57,686 (1969) 7 99.988 Rubella (congenital) 20,000 (1964-65) 1 99.995 Tetanus 601 (1948) 20 96.672 MMWR 2005;52(#54)
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0 20 40 60 80 100 120 140 160 1970 1975 1980 1985 1990 1995 2000 2005 Cases (thousands) Mumps—United States, 1968-2005* Year *2005 provisional total CDC/NIP, 2006
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0 2000 4000 6000 8000 10000 12000 14000 1980 1985 1990 1995 2000 2005 Cases Mumps—United States, 1980-2005* Year *2005 provisional total CDC/NIP, 2006
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0 10 20 30 40 50 60 70 1980 1985 1990 1995 2000 Percent Mum ps—Unit ed St at es, 1980-2003 Age Dist ribut ion of Report ed Cases 5-14 yrs 15-39 yrs <5 yrs > 40 yrs Year CDC/NIP, 2006
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MUMPS CURRENT OUTBREAK
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MUMPS OUTBREAKS Sporadic outbreaks occur Usual settings for outbreaks Schools, especially high schools and colleges Military bases Healthcare facilities
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MUMPS OUTBREAK, U.S. Ongoing since late 2005 >1,000 cases reported First cases recognized in Iowa now 9 states involved Most cases 18 – 25 years old Most persons have had at least 1 mumps vaccine
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