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Unformatted text preview: a.iii.3. b. Know that neurons along the D-V axis respond to the gradient of signals (BMPs dorsally and Shh ventrally) to differentiate b.i. Motor neurons are ventral (Shh induced) b.ii. Sensory neurons are dorsal (BMP induced) b.iii. Interneurons : Make connections between dorsal sensory and ventral motor neurons b.iii.1. Many types of interneurons b.iii.2. Respond to gradient of signals b.iv. c. Experiment : What if you took a piece of notochord and moved it up higher? c.i. Notochord is still releasing Shh c.ii. Result: Motor neurons form where interneurons should form c.iii. Can induce motor neurons on the basis of this gradient with Shh being most important for original placement of neurons. c.iv....
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- Fall '11
- Anatomy, Neural tube, SHH, motor neurons