11-07-11 Neuronal Cell Organization Continued

11-07-11 Neuronal Cell Organization Continued - ZOL 320...

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ZOL 320 Developmental Bio November 7, 2011 Neuronal Cell Organization Continued II. Cell organization in the neural tube A. Types of cells in neural tube B. Cell origins in the nervous system: C. Cell layers of the neural tube a. Large scale brain organization – from a single layer of germinal neuroepithelium: a.i. Cortex : Layer of cell bodies and axons a.ii. Ventricle : Lumen space a.iii. Nucleus : Ganglion – group of nerve cell bodies a.iv. Tract : Nerve – group of axons b. The original single germinal neuroepithelium layer forms a transitory three-layer structure: b.i. Inner ventricular layer (or zone) of dividing cells (closest to neurocoel where neuroepithelium was) b.ii. Middle intermediate (mantle) layer of cell bodies (lots of stoma) b.iii. Outer marginal layer of axons c. Development of neural tube walls c.i. c.ii. Spinal cord and medulla retain this organization c.iii. Meninges layer (not shown) surrounds the tube/spinal cord c.iii.1. Derived of mesoderm c.iii.2. Support of brain, protection c.iii.3. Blood vessels present in it c.iii.4. Doesn’t play functional role – just there for support. c.iv.
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11-07-11 Neuronal Cell Organization Continued - ZOL 320...

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