11-18-11 Integument and Mammary Glands Continued

11-18-11 Integument and Mammary Glands Continued - ZOL 320...

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ZOL 320 Developmental Bio November 18, 2011 Integument and Mammary Glands Continued I. Development of the skin a. Developmental origin and anatomy b. Regulation of differentiation II. Mammary Gland Development a. Developmental anatomy a.i. A modified sweat gland that can only develop along the ventral in the mammary ridge (milk line) a.ii. Embryonic phase: a.ii.1. Ectoderm cells (mammary bud) sinks into the dermal layer and forms an extension (the duct); later activates to form a lumen a.ii.2. Primary duct branches as it extends outward a.ii.3. The depressed opening will form the nipple a.ii.4. Testosterone from testes acts on the mesenchyme cells to block further duct formation in males a.iii. The developing mammary gland is responsive to estrogen but which cells are responsive: epithelial or stromal cells? a.iii.1. Devise experiment using mouse tissue to determine which cells, stromal or ductal epithelial cells or both, are the cells that receive the strogen signal. a.iv.
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This note was uploaded on 12/21/2011 for the course BIO 202 taught by Professor Brooks during the Fall '11 term at UCSB.

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11-18-11 Integument and Mammary Glands Continued - ZOL 320...

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