This preview has intentionally blurred sections. Sign up to view the full version.
View Full Document
Unformatted text preview: a) What is the probability of this particular sample configuration? b) What is the probability of observing an equal or greater number of heterozygotes? c) What is the probability of observing a smaller number of heterozygotes? d) What is the chisquared statistic for HardyWeinberg equilibrium? 3. Consider two loci in disequilibrium in a large population. Assume that the recombination fraction between the two loci is 0.01. In how many generations do you expect the disequilibrium coefficient D to be halved? 4. Consider the following set of haplotype frequencies: p AB = 0.3, p Ab = 0.2; p aB = 0.1; p ab = 0.4 a) Calculate D, D’ and ∆ 2 between the two markers. b) What is the probability that allele A will be present in a chromosome that carries allele b? c) What is the maximum possible value of r 2 for this marker pair?...
View
Full Document
 Fall '06
 STAFF
 Genetics, Evolution, Population Genetics, allele frequency pM

Click to edit the document details