lecture 2 - Science of Epidemiology Lecture 2 History of...

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1 Lecture 2 History of Epidemiology Science of Epidemiology o Recognition of a biologic basis of disease o Systematic methods for describing and summarizing disease o Quantitative assessment of disease Hippocrates o 460-377 BC o st Epidemiologist? o Described disease from a rational rather than supernatural basis o Malaria and yellow fever o Termed “epidemic” and “endemic” o Observation was key to understanding o Related disease to environment, time, and seasons John Graunt o First to employ statistics in the study of disease o Described characteristics of birth and death in London (1662) o Created mortality tables o Identified patterns in medical and social events Graunt’s Observations o More male deaths than female deaths o More male births than female births o Seasonal variation in birth and death data 1632: Top 10 Causes of Death in London o o Consumption o Fever o Collick, stone, and strangury o Flox and small pox o Bloody flux, and scowring o Dropsie and swelling o Convulsion o Childbed o Liver grown
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2 1900: Top 10 Causes of Death in U.S.A. o Pneumonia o Tuberculosis o Diarrhea, enteritis, and ulceration o Heart disease o Stroke o Chronic nephritis o Unintentional injury o Cancer o Senility o Diptheria Source: National Office of Vital Statistics, Dec. 1947 2001: Top 10 Causes of Death in U.S.A. o Heart disease o Cancer o Stroke o Liver disease and cirrhosis o Chronic lower respiratory tract disease o Accidents o Diabetes o Pneumonia and influenza o Alzheimer’s disease o Nephritis/nephrosis
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lecture 2 - Science of Epidemiology Lecture 2 History of...

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