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lec16-13 - and K close and there is opening of...

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KIN 205: Chapter 14, Cardiovascular Physiology: -60 -40 Phase 1: The first phase of depolarization is due to the entry of Na + and exit of K + via channels that are permeable to both Na + and K + . At -60 mV, the influx of Na + exceeds the outflux of K + and the cell depolarizes. Phase 2: As the cell depolarizes, the channels that are permeable to Na
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Unformatted text preview: + and K + close and there is opening of voltage-gated Ca 2+ channels that lead to influx of Ca 2+ and further depolarization. Phase 3: At the peak of the action potential, the Ca 2+ channels close and K + channels open. Phase 4: The repolarization is due to an efflux of K + . At -60mV, the K + channels are closed....
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