Unformatted text preview: Step 3. cAMP activates a cAMP-dependant protein kinase which in turns phosphorylates three distinct proteins: 1. Slow Ca 2+ channels, which result in their opening (entry of Ca 2+ ), 2. A sarcoplasmic reticulum protein that triggers the ATP-dependent Ca 2+ uptake, 3. Myosin which results in an increased rate of the cross-bridge cycle. The end result is an increased velocity of contraction. Figure 14-30...
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- Fall '09
- Cardiovascular Physiology, slow Ca2+ channels