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2810F10Q2Ans

# 2810F10Q2Ans - what fraction would be expected to be...

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__ ANSWERS __________________ ________________________________ Your name Your lab day and room number or TA name BioGD2810 Genetics Fall 2010 Quiz #2 Part I. (10 points; 2 points each) The frequencies in percent of the ABO blood group alleles in a Scottish population were computed to be I A = 20.62, I B = 7.56, and i = 71.83. Complete the chart below showing the expected phenotype frequencies in this population, assuming Hardy-Weinberg conditions: Blood type Phenotype frequency A 0.3387 B 0.1143 O 0.516 AB 0.0312 A Scottish man of blood type AB marries a Scottish woman of the same blood type. What is the probability that their first child will also be blood type AB? 0.5 = 1/2 Continued next page

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Part II. (10 points; 1 point each) The I A “allele” for the ABO blood groups actually consists of two subtypes, I A1 and I A2 , both of which can be considered to be “ I A ”. In a population of Maoris from New Zealand, 75% of the I A alleles are I A1 and 25% are I A2 . Among individuals of genotype I A i , and assuming Hardy-Weinberg equilibrium,
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Unformatted text preview: what fraction would be expected to be: Genotype Fraction I A1 i 0.75 = 3/4 I A2 i 0.25 = 1/4 Among individuals of genotype I A I A , what fraction would be expected to be: Genotype Fraction I A1 I A1 0.5625 I A1 I A2 0.375 I A2 I A2 0.0625 In the same Maori population, the frequencies of individuals with B or AB blood are both less than 1%, while the frequency of individuals with O type blood is 49%. Complete the chart below with an estimate (to the nearest 5%) of the expected genotype frequencies (assuming Hardy-Weinberg equilibrium) in the population as a whole. Genotype Genotype frequency I A1 I A1 0.0506 I A1 I A2 0.0338 I A2 I A2 0.0056 I A1 i 0.315 I A2 i 0.105 Extra Credit (2 points) In the spaces below, provide two possible explanations for the existence of any Maoris with B or AB type blood. Migration into New Zealand of rare individual(s) with I B allele from Central Asia New mutations to I B...
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2810F10Q2Ans - what fraction would be expected to be...

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