Necrotizing_Fasciitis

Necrotizing_Fasciitis - Necrotizing Fasciitis The Flesh...

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Necrotizing Fasciitis “The Flesh Eating Bacteria” Vic V Vernenkar, D.O. General Vascular Surgery St. Barnabas Hospital Bronx, N.Y.
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Background An insidiously advancing soft tissue infection. Widespread fascial necrosis. Polymicrobial Most closely linked group A beta- hemolytic. Most cases caused by other bacteria.
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Syndromes Type I is polymicrobial Type II is group A strep Type III is gas gangrene or clostridial necrosis. A variant of type I is salt water NF caused by vibrio species.
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Pathophysiology Organisms spread from sub Q tissues along superficial and deep planes, facilitated by bacterial enzymes and toxins. Infection causes vascular occlusion, ischemia, necrosis. Superficial nerves damaged, producing anesthesia. Septicemia ensues
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M1 and M3 surface proteins increase adherence of the bacteria to the tissues, protect from phagocytosis. Streptococcal pyrogenic exotoxins release
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This note was uploaded on 12/27/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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Necrotizing_Fasciitis - Necrotizing Fasciitis The Flesh...

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