Unformatted text preview: BUT: if base and leaving group are protonwill occur (see below) Oe) (cH:):co Na DMSO or hexane or diethyl ether section 9.1, 9.2, 9.4-9.8 OH E2 - notice strong and BULKY base and aprotic solvent ALSO reaction will favor formation of more substituted alkene and E-alkene (consider Newman projection and removal of proton antito leaving group) hindered removal of least hindered-Y= I Hzo : 3. .,.^\--\ ---==> SN1 ! (cHe)3coH : ______----------,.-\. .'\ heat E1 Spl - proceeds with racemization (notice protic solvent, poor nucleophile) OH-,'^\.4^\ E1 - favors more substituted alkene- and E alkene - bulky, weak base I...
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- Fall '11
- pH, Solvent, Diethyl ether, Tetrahydrofuran, Protic solvent, solvents