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Unformatted text preview: _ O more freedom in products + br therefore AS" would be (+) H.H z\/ ----------------morefreedom in starting material therefore AS" would be (-) NOTE: as temperature increase the AS" factor for determining AG" becomes more important Consider this: in the reaction of secondary alkyl halide with a nucleophile where the reaction may precede via either an SNl or SN2 process. Syl has more freedom in transition structure while SN2 has less (2 molecules are coming together in TS)! Therefore AS'would favor SN1. With this in mind, another way to select for SN2 wouldle-to-ea*qr-outlhe reaction at low temperaturet so that AS'is less important or, to [email protected]_ temperatures!...
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This note was uploaded on 12/27/2011 for the course CHEM 282 taught by Professor Nabylmerbouh during the Fall '10 term at Simon Fraser.
- Fall '10