29 - Gastrointestinal Viruses Viral Gastroenteritis It is...

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Gastrointestinal Viruses
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Viral Gastroenteritis It is thought that viruses are responsible for up to 3/4 of all infective diarrhoeas. Viral gastroenteritis is the second most common viral illness after upper respiratory tract infection. In developing countries, viral gastroenteritis is a major killer of infants who are undernourished. Rotaviruses are responsible for half a million deaths a year. Many different types of viruses are found in the gut but only some are associated with gastroenteritis.
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Associated with gastroenteritis Rotaviruses Adenoviruses 40 41 Caliciviruses 嵌嵌嵌嵌 Norwalk like viruses or SRSV (Small Round Structured Viruses) Astroviruses SRV (Small Round Viruses) Coronaviruses Toroviruses
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Found in the gut, not normally associated with gastroenteritis Polio Coxsackie A Coxsackie B Echo Enteroviruses 68-71 Hepatitis A Hepatitis E Adenoviruses 1-39 Reoviruses
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Found in the gut as opportunistic infection CMV HSV VZV HIV
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Gastrointestinal Viruses Virus Genome Typical disease incubation Duration Rotaviruses: Group A, B, C ds-segmented RNA Major cause of diarrhea in children 1-3 days 24-56 h 5-8 days 3-7 days Caliciviruses Norwalk agents ssRNA Infects adults and children Epidemic viral gastroenteritis 1-3 days 18-24 h 1-3 days 12-48 h EAd 40,41 Linear dsRNA diarrhea in children 7-8 days 8-12 d Astrovirus +ssRNA Infects mainly children and elderly 1-4 days 1-4 d
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29 - Gastrointestinal Viruses Viral Gastroenteritis It is...

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