GlucoseRegulationPancreasLiver

GlucoseRegulationPancreasLiver - Glucose Regulation What is...

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Glucose Regulation What is diabetes? Cells need sugar—ATP and the Krebs Cycle What comes in through the gut—basic nutrition Role of liver in processing nutrients, storing glucose Absorptive Pathways and role of insulin from pancreas Post-absorptive Pathways Understanding Diabetes
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Diabetes mellitus—”starvation amidst plenty” Type I Juvenile onset Pancreas beta cells die, no insulin produced Type II Adult onset Complicated set of factors, some insulin production Goal—understand why we need insulin
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Cells and Glucose All cells of body need constant glucose supply, especially nervous tissue Most other nutrients can be converted into glucose or derivatives for making ATP ATP is celluar “gasoline”
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Glycolysis and Kreb’s Cycle Main way that cells make ATP Glucose is principle reactant
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Why not eat just sugar?
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Essential Amino Acids Only additional nutrients that body can’t produce Needed for making proteins Also some vitamins and minerals must come from diet
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What happens to the rest of what we eat?
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Interconversion of Nutrients Almost everything we eat can be converted and used by Kreb’s cycle
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We need some other nutrients— essential amino acids, vitamins, minerals Our body also uses fats and proteins directly from diet Why not eat just sugar?
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GlucoseRegulationPancreasLiver - Glucose Regulation What is...

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