Kidney Function and Nephrons

Kidney Function and Nephrons - How does the kidney work?...

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How does the kidney work? What controls the rate and concentration of urine? Review nephron in kidney Steps in urine formation and concentration Glomerular filtration Reabsorption Tubular secretion
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Nephron is functional unit of kidney Over 1 million nephrons in human kidney Glomerulus is filtration site in cortex Tubules form loop of Henle, extending a few centimeters into medulla Reabsorption and secretion in tubules
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More realistic view of nephrons
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Filtration at Glomerulus Filtration membrane formed by podocyte cells lets all of plasma components of blood filter out of glomerular capillaries and into proximal convoluted tubule
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What happens to filtrate to make urine? Filtrate contains all non-protein and non-cellular parts of blood Water Dissolved ions Dissolved glucose Amino acids Nitrogenous wastes (nitrites, urea) No proteins No cells Production of urine and thus control of blood chemistry involves three processes Control over glomerular filtration rate (how fast is blood plasma filtering out of blood into tubules of kidney
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Kidney Function and Nephrons - How does the kidney work?...

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