Exam+2--W03 - Print Name Bio3l0 Introductory Biochemistry...

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Print Name 8-Digit ID Bio3l0 Introductory Biochemistry Winter Term 2003 Exam2 Write clearly. It is wrong if we can't read it For multiple choice: choose the best answer(s) for each problem Three Point Questions 1. Indicate which statement is correct: a. Hexokinase and glucokinase are isozymes, which differ in their localization but not in their K* for glucose b. The muscle is the organ specialized for keeping the blood glucose level constant c. The conversion of pyruvate to lactate is an irreversible reaction and catalyzed by the enzyme lactate dehydrogenase (LDH) d. None of the statements above is correct 2.Indicate which answer is correct: a. Glycogen phosphorylase catalyzes the phosphorolysis of cr-(1-a) glycosidic bonds starting at the reducing end of the glycogen b. Glucosidase activity of the debranchingenzyme is required to cleave cx (1-4) glycosidic bonds c. The reaction catalyzed by glycogen phosphorylase is: Glycogen (n) + ATP + Glycogen (n-1) + Glucose-l-P + ADP d. Dietary glycogen is hydrolyzed by amylase 3. During the signal transduction mechanism for stimulating an immune response to bacteria, protein kinase C is activated by increased levels of calcium and diacylglycerol in the cytosol. It is only one step in the mechanism, but the result is that each protein kinase C molecule phosphorylates many molecules of myosin light chain (one of its substrates) to increase cell motility. Which of the following features of BioSignaling Mechanisms best describes the phosphorylation step of this mechanism? a. Integration b. Desensitization c. Specificity d. Amplification e. Polarization 4. Which of the following is NOT a product derived from oxaloacetate? a. Phosphoenolpyruvate b. Pyruvate c. Acetyl-CoA d. Aspartate 5. The Asialoglycoprotein Receptor is a ligand-activated protein controlling certain reactions of carbohydrate metabolism. It is in the Receptor Enzyme Class. Given this information, which of the following processes would you expect this receptor to utilize during signaling after ligand bindingT a. Increased concentrations
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d. Only B and C insulin receptor and others in class characteristically have e. A, B and C these features 6. Indicate which statement is correct: a. Glucagon stimulates the storage of glucose as glycogen and increases glycolysis b. Type 2 diabetes is insulin independent and linked to obesity c. Glucose levels of the blood are kept fairly constant at about 20 mM d. GLUT1-5 are the 5 known isozymes of glutamine transferase 7. In most cases, the carboxyl terminus of transmembrane proteins is a. On the outside of the plasma membrane b. On the inside of the plasma membrane c. On the same side as any carbohydrate that is attached to the protein d. Always on the side of the membrane as any catalytic active sites of the protein e. A and C are both true
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This note was uploaded on 04/06/2008 for the course BIO 310 taught by Professor Unknown during the Spring '06 term at University of Michigan.

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Exam+2--W03 - Print Name Bio3l0 Introductory Biochemistry...

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