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Study Questions 24-28

Study Questions 24-28 - Study Questions 24-28 1 Describe...

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Study Questions 24-28 1. Describe the role of histone acetylation/deacetylation in regulation of transcription. 2. Describe the role of chromatin remodelling complexes in regulation of transcription. 3. Describe an influence of activators and repressors on assembly of initiation complexes. 4. Explain the role of enchancesomes and architectural proteins in regulation of transcription initiation? 5. Explain the role of mediators (or insulators different question) in regulation of transcription initiation. 6. What is the role of DNA methylation in regulation of transcription initiation? 7. Describe how TFs from nuclear receptors superfamily regulate transcription (one example is enough; remember: nuclear receptor could be in cytoplasm, bound to chaperone protein, or in nucleus, already bound to DNA) . 8. What is (are) the role(s) of transcription factors during development? 9. Describe the role of TBP during transcription (think about promoters for all three eukaryotic RNAPs and TATA-less RNAPII promoters
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