QUININ DIHYDROCLORID - QUININ DIHYDROCLORID Chinini...

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QUININ DIHYDROCLORID Chinini dihydrochloridum C 20 H 24 N 2 O 2 .2HCl P.t.l: 397,3 Quinin dihydroclorid là (8 S ,9 R )-6’-methoxycinchonan-9-ol dihydroclorid, ph i ch a t 99,0 đ n 101,0% ế C 20 H 24 N 2 O 2 .2HCl, tính theo ch ph m đã s y khô. ế Tính ch t B t tr ng hay g n nh tr ng. R t tan trong n c, tan trong ethanol 96%. ư ắ ướ Đ nh tính A. Ph ng pháp s c ký l p m ng (Ph l c 5.4). ươ ụ ụ B n m ng : Silica gel G (TT). Dung môi khai tri n : Diethylamin - ether - toluen (15 : 36 : 60 ). Dung d ch th : Dung d ch ch ph m 1,0% trong ế methanol (TT ). Dung d ch đ i chi u (1) ế : Dung d ch quinin sulfat chu n (ĐC) 1,0% trong methanol (TT ). Dung d ch đ i chi u (2) ế : Dung d ch ch a 1,0% c a m i quinidin sulfat chu n (ĐC) quinin sulfat chu n (ĐC) trong methanol (TT). Cách ti n hành
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This note was uploaded on 12/28/2011 for the course PHARMACEUT 101 taught by Professor Yentrang during the Spring '11 term at Albany College of Pharmacy and Health Sciences.

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QUININ DIHYDROCLORID - QUININ DIHYDROCLORID Chinini...

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