ALVERIN CITRAT - ALVERIN CITRAT Alverini citratum...

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ALVERIN CITRAT Alverini citratum C 20 H 27 N.C 6 H 8 O 7 P.t.l: 473,6 Alverin citrat là ethylbis(3-phenylpropyl)amin citrat, ph i ch a t 99,0 đ n 102,0% C ế 20 H 27 N.C 6 H 8 O 7 , tính theo ch ph m đã làm khô. ế Tính ch t B t k t tinh màu tr ng, ch y nhi t ộ ế ả ở đ kho ng 104 o C. Khó tan trong n c và ether, h i tan ướ ơ trong ethanol. Đ nh tính Ph h ng ngo i (Ph l c 4.2) c a ch ph m ph i phù h p v i ph h ng ngo i đ i chi u c a ổ ồ ụ ụ ế ổ ồ ạ ố ế alverin citrat chu n (ĐC). pH Dung d ch ch ph m 0,5% ph i có pH t 3,5 đ n 4,5 (Ph l c 6.2). ế ế ụ ụ T p ch t liên quan Xác đ nh b ng ph ng pháp s c ký l ng (Ph l c 5.3). ươ ụ ụ Pha đ ng: Dung d ch natri lauryl sulfat 0,01 M trong h n h p acetonitril - n c ướ (55 : 45), đi u ch nh pH đ n 3,0 b ng ế acid phosphoric (TT) . Dung d ch th
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This note was uploaded on 12/28/2011 for the course PHARMACEUT 101 taught by Professor Yentrang during the Spring '11 term at Albany College of Pharmacy and Health Sciences.

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ALVERIN CITRAT - ALVERIN CITRAT Alverini citratum...

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