THEOPHYLIN - THEOPHYLIN Theophyllinum C7H8N4O2 P.t.l.:...

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THEOPHYLIN Theophyllinum C 7 H 8 N 4 O 2 P.t.l.: 180,2 C 7 H 8 N 4 O 2 .H 2 O P.t.l.: 198,2 Theophylin laø 1,3-dimethyl-3,7 dihydro-1 H -purin-2,6-dion ôû daïng ngaäm moät phaân töû nöôùc hoaëc khan, phaûi chöùa töø 99,0 ñeán 101,0% C 7 H 8 N 4 O 2 tính theo cheá phaåm khan. Tính chaát Boät tinh theå traéng. Khoù tan trong nöôùc, hôi tan trong ethanol, tan trong caùc dung dòch hydroxyd kieàm, amoniac vaø caùc acid voâ cô. Ñònh tính Coù theå choïn moät trong hai nhoùm ñònh tính sau: Nhoùm I: A, B, D. Nhoùm II: A, C, D, E. A. Ñieåm chaûy (Phuï luïc 6.7) cuûa cheá phaåm (ôû daïng ngaäm moät phaân töû nöôùc phaûi saáy khoâ ôû 100 ñeán 105 ° C, ôû trong khoaûng 270 ñeán 274 ° C. B. Phoå haáp thuï hoàng ngoaïi (Phuï luïc 4.2) cuûa cheá phaåm sau khi saáy khoâ ôû 100 ñeán 105 ° C phaûi phuø hôïp vôùi phoå haáp thuï hoàng ngoaïi cuûa theophylin chuaån (ÑC). C. Ñun 10 mg cheá phaåm
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THEOPHYLIN - THEOPHYLIN Theophyllinum C7H8N4O2 P.t.l.:...

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