Ampicilin trihydrat - AMPICILIN TRIHYDRAT Ampicillinum...

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AMPICILIN TRIHYDRAT Ampicillinum trihydratum H N O N S CH 3 COOH H CH 3 NH 2 O H H . 3H 2 O C 16 H 19 N 3 O 4 S. 3H 2 O P.t.l: 403,5 Ampicilin trihydrat là acid (6R)-6-( α -D-phenyl- glycylamino) penicilanic trihydrat ph i ch a t 96,0 đ n 100,5% C ế 16 H 19 N 3 O 4 S, tính theo ch ph m khan. ế Tính ch t B t k t tinh tr ng, ế khó tan trong n c, th c t không tan trong ethanol 96% và d u béo. Tan trong dung d ch acid loãng ướ ế và dung d ch hydroxyd ki m loãng. Đ nh tính Có th ch n m t trong hai nhóm đ nh tính sau: Nhóm I: A, D Nhóm II: B, C, D A. Ph h ng ngo i (Ph l c 4.2) c a ch ph m ph i phù h p v i ph h ng ngo i c a ụ ụ ế ampicilin trihydrat chu n (ĐC). Các phép th B, C, D đ c ti n hành nh đã mô t chuyên lu n "Ampicilin". ượ ế ư ả ở Đ trong c a dung d ch, pH, góc quay c c riêng, t p ch t liên quan; N, N - dimethylanilin, tro sulfat: Ph i tuân theo các yêu c u và ti n hành th nh đã mô t trong chuyên lu n "Ampicilin". ế ư
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