week4 Knowledge check.docx - Define SIAD and patient characteristics that may have contributed to development of SIAD Syndrome of inappropriate

week4 Knowledge check.docx - Define SIAD and patient...

This preview shows page 1 - 3 out of 7 pages.

Define SIAD and patient characteristics that may have contributed to development of SIAD Syndrome of inappropriate antidiuretic hormone (SIADH) secretion is characterized by high levels of ADH in the absence of normal physiologic stimuli for its release(McCance & Huether, 2019). Basically, it's the over secretion of ADH from the pituitary with an unknown etiology. Our patient is at risk for acquiring SIADH as she is currently taking hypoglycemic medications, antidepressants/antipsychotics, and is elderly. She is also a smoker, which contributes to pulmonary disorders such as pneumonia, which is commonly associated with SIADH. McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier. Why the patient had the symptoms of hypocortisolism? Hypocortisolism develops because of a primary inability of the adrenals to produce and secrete the adrenocortical hormones (McCance & Huether, 2019). She has RA for 20 years plus the extended use of prednisone; in addition, her symptoms maybe the result of stress placed upon her by exacerbation of chronic RA. Classic symptoms of hypocortisolism begin with weakness and fatigue, hyperpigmentation. Hormone and mineral corticoid deficiency symptoms include hypotension, hypovolemia, dizziness, and hyperkalemia. McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier. Role of parathyroid hormone in the development of primary hyperparathyroidism. Hyperparathyroidism is characterized by greater than normal secretion of parathyroid hormone (PTH) and hypercalcemia (McCance & Huether, 2019). Primary hyperparathyroidism is caused by PTH secretion uncontrolled by the usual feedback mechanisms, resulting in abnormally high levels of calcium in the blood, as indicated in our patients' labs. The high calcium is cased by increase reabsorption, and Gi absorption of calcium yet fails to stop PTH secretion. McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier. Renal stone formation in a patient with hyperparathyroidism? High levels of calcium in the bloodstream result in hypercalciuria, which also affects renal function, causing metabolic acidosis, thus producing alkaline urine. PTH over secretion contributes to phosphate extraction, inducing hypophosphatemia, and hyperphosphatemia, which leads to the formation of renal calculi. McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier. Hyperparathyroidism at risk for bone fracture?
Image of page 1
Hyper osteoclastic and osteocytic activity results in an increase in the bone absorption of calcium. This increased absorption of calcium weakens the bone, thus putting the patient more at risk for done breakage and kyphosis.
Image of page 2
Image of page 3

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture