fatmetabolism - Fat Metabolism Im not fat, Ive just got a...

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Fat Metabolism I’m not fat, I’ve just got a lot of potential energy!
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Digestion, Mobilization, and Transport http://courses.cm.utexas.edu/emarcotte/ch339k/fall2005/Lecture-Ch17-1/Slide2.JPG
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Emulsification Fats are not water soluble Made into bile salts that are Absorbed as micelles in small intestines
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Chylomicron Carriers proteins that carry fats stored in adipose tissue
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Role of Hormones Can mobilize from adipose Release as Fatty acids Epinephrene and glucagon release cAMP make fatty acids and glycerol mobilizes fat
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Animation of Process http://www.wiley.com/legacy/college/boyer/0470 FUN!
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Activation and Transported to Mitochondria FA + CoASH --> ATP = FA-SCoA + AMP + Ppi Driven by breakup of Ppi Acyl CoA Synthetase -32.5 kJ Transported through inner mitochondrial membrane via carnitine uses specific acyl carnitine transporter
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Carnitine N + CH 2 C H 3 CH 3 CH 3 CH CH 2 OH C O O
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Formation of acyl carnitine N + CH 2 C H 3 CH 3 CH 3 CH CH 2 OH C O O CoAS C R O carnitine acyl CoA N + CH 2 C H 3 CH 3 CH 3 CH CH 2 O C O O C R O CoASH acyl carnitine + + Can get transported across inner mitochondrial membrane
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Animation of Process http://www.brookscole.com/chemistry_d/template /student_resources/shared_resources/animations/c
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This note was uploaded on 12/28/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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fatmetabolism - Fat Metabolism Im not fat, Ive just got a...

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