nucleotides - Nucleic Acids The blueprints Types of...

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Nucleic Acids The blueprints
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Types of Molecules Polymers of nucleotides DNA: code for genetic information RNA mRNA intermediates in protein synthesis rRNA carry out protein synthesis tRNA translate info on mRNA into a.a. Gene
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Nucleotide Components Bases + sugar + phosphate Bases purine adenine guanine pyrimidines thymine cytosine uracil
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Bases N N N N NH 2 N N N N O NH 2 N N O O C H 3 N N O NH 2 N N O O Adenine (A) Guanine (G) Purines Pyrimidines Thymine (T) (DNA only) Cytosine (C) Uracil (U) (RNA only)
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Nucleotide Components Sugars ribose Deoxyribose Rings numbered using primes C1 = 1’ etc • PO 4 3- OH OH O H O HOH 2 C OH H O H O HOH 2 C ribose (RNA) 2-deoxyribose (DNA)
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Nucleotide Structure Base-sugar-phosphate Base attached to C1 of sugar Note sugar is β Phosphate attached to C5 of sugar Usually nucleotides are triphosphates, but can be mono or di O H P O O O P O O O P O O O N O N N OH OH N NH 2 O H P O O O P O O O P O O O O H OH N N O O C H 3 Adenosine Triphosphate (ATP) (a ribonucleotide) Thymidine Triphosphate (TTP) (a deoxyribonucleotide)
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Nucleic Acid, a polymer of nucleotides
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Nucleic Acids Polymer of nucleotides Phosphodiester linkage 3’ of one sugar to 5’ of other vectorial Sequence read 5’ - 3’ Previous slide is C-A-A Next slide (a cartoon drawing) is A-T-G-C
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This note was uploaded on 12/28/2011 for the course STEP 1 taught by Professor Dr.aslam during the Fall '11 term at Montgomery College.

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nucleotides - Nucleic Acids The blueprints Types of...

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