Cells160-page12

Cells160-page12 - cytoplasm. Rough ER has connections to...

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Cell - 12 Endoplasmic Reticulum Series of interconnected membrane-enclosed flattened tubes or channels and sacs that compartmentalize the cytoplasm, and run throughout the cytosol. Projections of endoplasmic reticulum connect the nuclear envelope with the endoplasmic reticulum and other projections connect to the plasma membrane. Endoplasmic reticulum synthesizes, transports and isolates intracellular contents There are two forms of endoplasmic reticulum: smooth and rough. Rough Endoplasmic Reticulum Endoplasmic reticulum that has ribosomes attached to its surface is called rough endoplasmic reticulum. This is most abundant in cells that secrete many proteins. Rough ER is often found in sheets or layers of flattened sacs within the
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Unformatted text preview: cytoplasm. Rough ER has connections to the nuclear envelope Proteins synthesized at the ribosomes of cells that secrete proteins, such as digestive enzymes or hormones, transport the proteins through the rough endoplasmic reticulum channels. Small signal peptide sequences during protein synthesis are responsible for moving the polypeptide into the ER for modification and transport. Proteins accumulate in pockets in the ER that break off forming transport vesicles for export. Rough endoplasmic reticulum may synthesize itself, and also can be used to maintain and replace nuclear or plasma membrane as needed....
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This note was uploaded on 12/29/2011 for the course BIO 151 taught by Professor Edwards during the Spring '10 term at SUNY Stony Brook.

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