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Cells160-page19 - • Microfilaments(Actin Filaments •...

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Cell - 19 Cytoskeleton The cytoskeleton is the internal, fibrous framework of cells. Many organelles and some enzymes are organized along this framework. The cytoskeleton maintains the shape of cells (animal) by its architectural design and anchors organelles within the cytosol. The cytoskeleton is responsible for motility within cells, such as muscle contraction and cyclosis, the internal motion of the cytoplasm. Organelles may be transported along cytoskeletal tracks within the cytosol Vesicles are moved along cytoskeletal tracks for both import and export. The cytoskeleton can also be responsible for motility of cells and external movement such as the amoeboid movement of white blood cells and the migration of cells during development. The cytoskeleton also has a role in cell division. Components of the cytoskeleton Microtubules
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Unformatted text preview: • Microfilaments (Actin Filaments) • Intermediate Filaments Microtubules • Hollow cylindrical tubules composed of tubulin, a dumbbell shaped protein. • Can generate movement as microtubule aggregates slide past one another. • In animal cells, microtubules develop from the centrosome or microtubule organizing center. The growth of microtubules is determined by the tubulin organization and accessory proteins that cap microtubules to stabilize them. • Some plants produce toxins that inhibit the production of animal microtubules, blocking cell division. This is an excellent plant defense. Taxol, a terpene produced by the Pacific yew, is used in cancer treatment. • Microtubules form the spindle apparatus, which separates chromosomes during cell division with the assistance of kinesins, motor proteins....
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