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DNA160-page5 - the volume of DNA in the nucleus for normal...

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DNA: Structure and Replication - 5 Long chains of nucleotides could be formed linking sugar-phosphate backbones with the Nitrogen bases attached to the side of the sugar molecules (S-P-S-P-S-P-S-P, etc.). . Specifically, the phosphate bonded to the 5' carbon of the sugar molecule, leaving the 3' carbon of the sugar to attach to the next phosphate. The nitrogen base attached to the 1' carbon of the sugar molecule. This little detail is important to the structure of DNA. In a carbon compound, each of the carbons is given a number. Deoxyribose is a 5-carbon sugar. Who bonds to what carbon is critical to DNA's structure. 2. Mirsky restated work from the 1850's that determined the relationship of
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Unformatted text preview: the volume of DNA in the nucleus for normal body cells, cells just prior to division and in gametes. This provided evidence that DNA was the genetic molecule because it corresponded with the behavior of chromosomes in mitosis and meiosis. 3. Erwin Chargaff's work in 1947: • The four nitrogen bases were not present in equal amounts • The amounts differed in different species • But • The amount of Adenine was always the same as Thymine • The amount of guanine was always the same as Cytosine This information is known as Chargaff's rules...
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