DNATechnology160-page7 - The variations in the DNA...

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Biotechnology - 7 One of the reasons we can use DNA probes is that all individuals have a type of DNA called short tandem repeats or STRs. STRs are non-coding DNA that consist of 2 – 5 nucleotide sequences repeated many times (in tandem). Their number and arrangement in human chromosomes is unique to each individual. Forensic medicine, for example, uses STRs in DNA analysis, and have a common set used in their work. When a DNA sample is tested for a set of 10 STRs, the chance of two people having the same profile is less than 1 in 1 trillion. Isolating the Desired DNA from a DNA Gene Library Target genes can also be isolated using gel electrophoresis.
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Unformatted text preview: The variations in the DNA sequences between individual DNA samples are determined by differences in restriction enzyme cleavage patterns called restriction fragment length polymorphisms or RFLPs.) These different DNA fragments can be separated using gel electrophoresis and then isolated for closer study using additional techniques. Gel electrophoresis is a common practice in gene analysis, for basic research, for medical research and for forensic study. Gel electrophoresis may be used together with DNA probes and other techniques to more readily identify target DNA sequences....
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