DNATechnology160-page17

DNATechnology160-pag - Stem cells from umbilical cord blood are harvested and the ADA gene is inserted using a retrovirus Introduced into a

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Biotechnology - 17 Mouse heart cells have been cultured from embryonic stem cells, and have been successfully transplanted into damaged heart tissue. There is promise that the technique could work in humans, too. The gene needed for preventing severe combined immunodeficiency disorder has been successfully transferred to bone marrow cells of children who have this genetic disease. (The gene codes for a critical enzyme, ADA, needed to activate the immune system cells.)
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Unformatted text preview: Stem cells from umbilical cord blood are harvested and the ADA gene is inserted using a retrovirus. Introduced into a genetically "impaired" child, the altered cells carry the needed gene to bone marrow, implant there and produce the needed enzyme. Other diseases in which gene therapy is being attempted include: • Cystic fibrosis • Hemophilia • Muscular Dystrophy • Some cancers • Hypercholesterolemia • Rheumatoid arthritis...
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This note was uploaded on 12/29/2011 for the course BIO 151 taught by Professor Edwards during the Spring '10 term at SUNY Stony Brook.

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