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Energy160-page11 - present • Some enzymes are...

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Energy Flow in Cells - 11 Enzymes and Their Environment - Enzyme Regulation Enzyme activity is controlled by conditions of the environment. Each enzyme works at precise pH, temperature and chemical conditions, such as the amount of sodium ions in the cell. Enzyme Regulation Enzyme regulation a natural part of how cells function. Homeostasis in cells and organisms involves elaborate feedback mechanisms. They are essential for control of metabolism and the orderly operation of cells. Many of these metabolic controls work by activating or de-activating enzymes at appropriate times. This is the subject of enzyme regulation. The amount of enzyme present can serve to regulate the rate of some chemical reactions. And the cell's DNA controls whether an enzyme is
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Unformatted text preview: present. • Some enzymes are manufactured in an inactive form, and converted to an active form only in the presence of the proper reactant (substrate). • Regulating enzyme activity often involves "sophisticated" controls. Allosteric Regulation Some enzymes have specific receptor sites that change its shape to either activate the enzyme or inhibit the enzyme from functioning. These molecules are known as allosteric regulators. The receptor site on the enzyme is called the allosteric site. One allosteric site may activate by stabilizing the enzyme shape for the active site and another may inhibit by stabilizing an inactive shape of the enzyme....
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