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GeneRegulation160-page10 - The signals trigger cell...

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Gene Regulation - 10 Pattern Formation and Homeotic Genes During development different cells become organized in predictable patterns, some of which are determined by organization of the egg cell cytoplasm, some by cell position within the embryo. Plant cell differentiation is almost exclusively positional. Their position in the meristems fixes their ultimate position and function. Animals have pattern formation, too, and often once pattern is induced, it is fixed. Cells transplanted from one position to another in the embryo may develop into the structure to which they were patterned prior to the transplant. Chemical signals are used extensively during pattern formation.
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Unformatted text preview: The signals trigger cell responses that affect gene transcription of what are called "master genes", genes that control developmental sequences. Homeotic genes are a group of master genes that determine body-part identity and pattern development. There is a remarkable similarity of homeotic genes among different animals. The HOM genes of the fruit fly and the set of HOX genes in the mouse determine similar pattern development. Mutations in the homeotic genes produce organisms with misplaced body parts. Normal Fly Mutant Antennapedia Gene Eye Induction Mutant Targeted Gene Expression...
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