HumanInheritance160-page3

HumanInheritance160-page3 - • The partial sickle effect...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Human Inheritance Patterns - 3 Some Examples of Human Recessive Alleles that Cause Problems Cystic Fibrosis Affects a chloride ion channel membrane protein. Lack of the protein results in thickened excess mucus production, especially in lungs and pancreas. One recent experimental treatment involved gene therapy using genetically altered cold viruses that contain the normal gene. The viruses are sprayed into the nasal passages. When the virus invades the nasal mucus producing cells, the gene is incorporated into the cells and gets transcribed. The treatment is short-lived, however, since cells are replaced every few weeks. Sickle Cell Anemia Hemoglobin takes on a shape in low oxygen conditions that alters the shape of rbcs, causing clumping and rbc fractures that block blood flow. Treatment by periodic whole blood transfusions
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: • The partial sickle effect of heterozygotes does not negatively affect health, and confers some resistance to the malaria-causing protist. The correlation of sickle cell anemia and malaria is striking. • Tay-Sachs Disease • Inability to produce critical lipases, which results in accumulations of particular lipids in the brain. Tay-Sachs is fatal in early childhood. Carriers produce sufficient enzyme to not exhibit symptoms of Tay-Sachs. • Phenylketonuria • Inability to process the amino acid, phenylalanine • Protein intake must be critically monitored to prevent buildup of the amino acid to harmful concentrations. • Albinism • Inability to produce any melanin pigment • Treatment is to avoid sun and other bright light...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern